CLINICAL CASE OF HEREDITARY ANGIONEUROTIC DOMESTIC, CAUSED BY DEFICIENCY IN THE C1 COMPLEMENT SYSTEM

Abstract

The article is devoted to hereditary angioedema. Clinical cases of patients with hereditary angioedema identified in the Republic of Kazakhstan are presented. The data of anamnesis, clinical and laboratory-instrumental indicators in patients were evaluated; the polymorphism of clinical and anamnestic data is emphasized, which does not allow to establish specific syndromes in a timely manner and determine the clinical diagnosis, which, due to delayed diagnosis, leads to the late appointment of specific basic treatment, preventive measures and preventive intervention in connection with traumatic life and medical situations, leading to life-threatening states. The main clinical manifestations of hereditary angioedema are recurrent dense edema that persists for 25 days. The most involved human organs are the skin, upper respiratory tract and gastrointestinal tract. Clinical manifestations vary dramatically between patients, from asymptomatic to life-threatening edema, resulting in human and economic losses.