Chiral Analyses of Pollutants by Capillary Electrophoresis

I. Ali, T. Khan, H. Aboul‐Enein, I. B. Kuznetsov, Asim Mohd
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引用次数: 6

Abstract

The determination of enantiomeric composition of chiral xenobiotics and pollutants is a very difficult job due to their low amounts and poor detection by commonly used UV detector. But this sort of analysis is an important issue from the health point of view. The chiral analyses of these notorious pollutants by capillary electrophoresis have been discussed in this article. This review discusses the new trends and advancements, which have been achieved in the analyses of chiral pollutants using capillary electrophoresis and the state-of-art of their enaniomeric resolution. This article focuses on sample treatment, applications, optimization, detection, mechanisms of chiral resolution and future perspectives of CE in chiral resolution of xenobiotics. Besides, efforts have also been made to suggest the improvement in CE machine to make it ideal for the analyses of chiral xenobiotics at trace levels.
毛细管电泳分析污染物的手性
手性外源药物和污染物的对映体组成的测定是一项非常困难的工作,因为它们的数量少,常用的紫外检测器检测效果差。但从健康的角度来看,这种分析是一个重要的问题。本文讨论了毛细管电泳法对这些污染物质的手性分析。本文综述了毛细管电泳分析手性污染物的新趋势和新进展,以及毛细管电泳拆分手性污染物的技术现状。本文重点介绍了样品处理、应用、优化、检测、手性分辨机制以及CE在外源药物手性分辨中的应用前景。此外,还对CE仪进行了改进,使其成为痕量手性外源药物分析的理想仪器。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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