Intestinal tuberculosis complicated by pulmonary embolism and deep vein thrombosis

M. Abdulla
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Abstract

Venous thromboembolism (VTE) secondary to tuberculosis (TB) is a rare complication that can occur either at the time of presentation or later in the course of the disease. A 24-year-old woman was admitted with low-grade fever, abdominal pain, abdominal distension, and loose stools for one and half months. She was evaluated and diagnosed with abdominal TB. On the second day of admission, she had a sudden onset of the right lower limb edema with pain followed by breathlessness. Contrast-enhanced computed tomography of the thorax showed a thrombus in the left pulmonary artery. She was treated with low-molecular-weight heparin and started on anti-TB drugs. She was continued on oral anticoagulation with warfarin. We describe a patient who developed pulmonary embolism and lower limb deep vein thrombosis secondary to abdominal TB without paraaortic lymphadenopathy and a negative procoagulant workup, which was not reported previously. The mechanisms of VTE in TB are complex and may need further studies in the future, which may help the clinicians develop appropriate strategies for treatment.
肠结核并发肺栓塞和深静脉血栓
继发于肺结核(TB)的静脉血栓栓塞(VTE)是一种罕见的并发症,可发生在发病时或病程后期。24岁女性因低烧、腹痛、腹胀、稀便1个半月入院。她被评估并诊断为腹部结核。入院第二天,患者突然出现右下肢水肿并疼痛伴呼吸困难。胸部电脑断层造影显示左肺动脉有血栓。她接受了低分子肝素治疗,并开始服用抗结核药物。继续口服华法林抗凝治疗。我们描述了一位患者,他发展为肺栓塞和下肢深静脉血栓继发于腹部结核,没有主动脉旁淋巴结病和阴性的促凝血检查,这是以前没有报道的。静脉血栓栓塞在结核病中的机制是复杂的,未来可能需要进一步的研究,这可能有助于临床医生制定适当的治疗策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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