Diabetic Foot Ulcer (DFU) and Its Pharmaceutical and Therapeutic Strategies: A Systematic Review

Abstract

Introduction: One of the complications of diabetes is diabetic foot ulcers which is very common in these patients. Given that in Studies, found that diabetic foot complications increase with age. Therefore, considering the importance of diabetic foot ulcer treatment in diabetic patients, this systematic review was conducted on Diabetic foot ulcer (DFU) and Its pharmaceutical and therapeutic strategies. Materials and Methods: In this systematic review, this integrated overview study was conducted based on the Broome method. The present study is a systematic review article that was conducted in English and Persian by searching articles in search engines, scholar, PubMed, Springer's reputable scientific sites and databases. Using the articles published in the last 20 years, it was based on the most important treatments for diabetic foot ulcers. In the first stage, 39 papers were found. Of these, 11 articles related to the topic that was published in the last 20 years were reviewed. Results: In this study, several methods for the treatment of diabetic foot ulcers have been investigated. In a study, in the treatment of chronic ulcers of grade 3 diabetes mellitus based on Wegener's classification, ultrasound waves of low frequency with standard care of the wound compared with standard care from scarring alone initially caused Accelerated recovery of chronic diabetic foot ulcers especially in the second and third months, while after 6 months of follow up, there was no significant difference in wound healing. Conclusion: In this study, as stated, our goal is to examine diabetic foot ulcer and their therapeutic and therapeutic strategies, that the results of various studies show that there are several therapeutic and therapeutic methods for treating diabetic foot ulcers. It is recommended that with screening and blood glucose control, prevent ulcers that cause amputation of the foot.