Tumours of the central nervous system

Abstract

Tumours of the central nervous system (CNS) are characterized by a remarkable diversity of pathological type and behaviour. Although rare, they affect people of all ages and hence have a disproportionate influence on the number of years of life lost to cancer. After many years of therapeutic stagnation, there have recently been some important improvements in molecular classification, treatment, and outcome. This chapter covers tumours of the CNS. Coverage of primary brain tumours includes: clinicopathology, presentation and general management, surgical management, radiotherapy, chemotherapy and new agents, and outcome/management of recurrence. The chapter also covers treatment options and outcomes for brain metastases and spinal cord tumours.