ACTIVE CONSTITUENTS OF PLANTS WITH HYPOGLYCEMIC POTENTIALS

R. Fayzullina, A. Akhmetyanova, N. Kudashkina
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Abstract

Now in medical community are even more often discussed such concept as the complementary medicine (CM) and its integration into conventional medicine. One of the most widespread directions of CM is phytotherapy which is regulated by allowing documentation of bodies of health care and consequently it is included in conventional medicine. A serious problem of world health care is the diabetes mellitus. According to data of the International Diabetes Federation (IDF) for 2015, in the world there are 415 million people have the diagnosis a diabetes mellitus and by 2040 increase in number of patients up to 642 million. In Russian Federation 12,1 million people are sick a diabetes mellitus. For prophylaxis and at early stages of development of a diabetes mellitus of the 2nd type phytotherapy is recommended. Now there is the active searching of plants with hypoglycemic activity. The pharmacological effect of plants is caused by the biologically the active materials (BAM) which are their part which are very various on structure and, respectively, on the effect which had by them. The review of results of the researches confirming presence of hypoglycemic activity at the BAМ, most widespread in flora is provided in article (phenolic substances, polysaccharides, alkaloids, etc.), mechanisms of their action are described. The submitted data demonstrate that from a position of evidential medicine searching and development of the new means of a phytogenesis allowing to expand the range of the medicines applied at a diabetes mellitus are expedient. At the same time the greatest effect of phytotherapy can be reached when using the multicomponent herbal teas containing a larger range of BAM in comparison with individual plants that will allow to influence pathogenetic processes of a disease.
具有降血糖潜能的植物活性成分
现在医学界更经常讨论补充医学(CM)及其与传统医学的融合等概念。中医最广泛的方向之一是植物疗法,通过允许医疗保健机构的文件管理,因此它被纳入传统医学。糖尿病是世界卫生保健的一个严重问题。根据国际糖尿病联合会(IDF) 2015年的数据,全球有4.15亿人被诊断为糖尿病,到2040年,患者人数将增加到6.42亿。在俄罗斯联邦,有1千1百万人患有糖尿病。对于糖尿病的预防和早期发展阶段,建议采用植物疗法。现在人们正在积极寻找具有降血糖作用的植物。植物的药理作用是由生物活性物质(BAM)引起的,这些生物活性物质是植物的一部分,它们的结构和作用各不相同。本文综述了在植物群中分布最广的植物BAМ中存在降糖活性的研究结果(酚类物质、多糖、生物碱等),并对其作用机制进行了描述。提交的数据表明,从循证医学的角度来看,寻找和开发植物发生的新方法可以扩大糖尿病药物的应用范围。与此同时,与单个植物相比,当使用含有更大范围BAM的多组分草药茶时,可以达到植物疗法的最大效果,这将允许影响疾病的发病过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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