FORMULASI DAN UJI FISIK GEL HANDSANITIZER EKSTRAK ETANOL DAUN SALAM (Syzygium Polyanthum) DENGAN VARIASI KONSENTRASI CARBOPOL

Jayanti Djarami, Aulia Debby Pelu, Ainun Pamana
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Abstract

The COVID-19 pandemic has made hand sanitizer gel widely used.  Hand sanitizer gels generally contain alcohol as an antiseptic to kill bacteria, but long-term use of antiseptics containing alcohol can cause skin irritation.  So we need natural alternative materials that have antibacterial power but are friendly to the skin and do not cause irritation.  One of theplants that can be used as an antibacterial is a bay leaf (Syzygium polyanthum) because it contains flavonoids that can act as an antiseptic against bacteria. The purpose of this study is to find out the formulation and physical test of the gel hand sanitizer of the ethanol extract of bay leaves (Syzygium polyanthum) with a variety of carbopol concentrations. this study used an experimental design.  Three formulations were made with different concentrations of carbopol, namely formula I (carbopol 0.5%), formula II (carbopol 1%), and formula III (carbopol 1.5%).  Of the three formulas, physical properties were evaluated which included organoleptic tests, homogeneity tests, and PH tests.  The results showed that formula I (carbopol 0.5%), and formula II (carbopol 1%) met the requirements for evaluating the physical properties of the hand sanitizer gel which included organoleptic tests, homogeneity tests, and PH tests.  While formula III (carbopol 1.5%) did not meet the physical test, namely the PH test.
月桂醇乙醇提取物(Syzygium Polyanthum)的配方和物理测试采用不同的CARBOPOL浓度
新冠肺炎疫情使洗手液被广泛使用。洗手液凝胶通常含有酒精作为杀菌剂来杀死细菌,但长期使用含有酒精的杀菌剂会引起皮肤刺激。所以我们需要天然的替代材料,具有抗菌能力,但对皮肤友好,不会引起刺激。其中一种可以用作抗菌的植物是月桂叶(Syzygium polyanthum),因为它含有类黄酮,可以作为细菌的防腐剂。本研究的目的是找出不同浓度月桂叶乙醇提取物的凝胶洗手液的配方和物理试验。本研究采用实验设计。以卡泊泊0.5%卡泊泊配制3种不同浓度的制剂,分别为式I(卡泊泊泊0.5%)、式II(卡泊泊1%)和式III(卡泊泊1.5%)。对这三种配方进行了物理性能评估,包括感官测试、均匀性测试和PH测试。结果表明,配方I(0.5%卡泊泊尔)和配方II(1%卡泊泊尔)满足评价洗手液凝胶物理性能的要求,包括感官测试、均匀性测试和PH测试。而公式III(卡泊泊1.5%)不符合物理测试,即PH测试。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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