HIV: reticulo-endothelial disorders

Abstract

This chapter discusses the blood disorders seen in patients living with HIV. HIV can directly affect the production of blood cells and the treatment of HIV may also lead to blood disorders rarely. The epidemiology of anaemia, thrombocytopaenia, and neutropaenia are outlined together with the key investigations needed when patients are found with these abnormalities. Infection, malignancies, and nutritional deficiencies as causes of haematological abnormalities are reviewed. The treatment of these conditions is outlined. The chapter also reviews the problems seen with coagulation in HIV. HIV-associated lymphadenopathy is discussed and the differential diagnosis of lymphadenopathy in people living with HIV are outlined.