New observations on the distribution of an old and forgotten model of enteritis in rats.

Abstract

Human serum injected intravenously into rats caused multiple foci of acute enteritis. The enteritis had a predilection for the antimesenteric side of the intestine and for the zones between circumferential vessels. Despite their antimesenteric location, Peyer's patches tended to be spared. The details of distribution suggest that a gradient related to intestinal blood flow plays a role in development of the enteritis.