Clinical and epidemiological features of viral infections in the children's non-infectious multidisciplinary medical organization

Abstract

The article presents generalized clinical and epidemiological features of viral infections in children's noninfectious multidisciplinary hospital based on the results of a multi-year comprehensive study. The study was conducted for 12 years (2006–2017), included 16615 patients, including those diagnosed with «Acute respiratory viral infection» – 6104 patients, with a diagnosis of «Acute intestinal viral infection» – 1934 patients. A total of 193017 microbiological studies were conducted, including molecular genetic studies. It was found that the overall incidence of viral infections in children's non-infectious multidisciplinary hospital was 21.1 [95% CI 20.3-21.9] per 1000 hospitalized patients (according to long-term average data). The main nosological groups of viral infections were respiratory infections, enteric infections, intrauterine infections and parenteral viral hepatitis. Viral infections in in children's non-infectious multidisciplinary hospital were characterized by the following clinical and epidemiological features: high incidence; age group at risk – children under 3 years; features of clinical picture with «masks» of noncommunicable pathology; presence of combined infections; high level of virus transmission; high frequency of infections, brought into the hospital; prevalence of healthcare-associated infections in the general structure of morbidity with outbreak and involvement in the epidemic process of children and adults; uneven distribution of morbidity and carriers in departments; presence of nosocomial circulation of viruses.