A Review on Chemistry of Anti-malarials

P. M. Chandira, CH. Nvs Mastanrao, B. Venkateswarlu
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引用次数: 0

Abstract

Malaria remains an important public health concern in countries where transmission occurs regularly, as well as in temperate areas and it is a major global health problem, with an estimated 500 million clinical cases occurring annually. Malaria is a complex disease that varies widely in epidemiology and clinical manifestation in different parts of the world. The most prevalent and dangerous type of malaria is caused by Plasmodium falciparum. P. vivax is a common cause of malaria in Latin America, Asia, and Oceania, but not Africa. P. malaria and P. ovale are much less common. Antimalarials are used in three different ways: prophylaxis, treatment of falciparum malaria, and treatment of non-falciparum malaria. Prophylactic antimalarials are used almost exclusively by travelers from developed countries who are visiting malaria-endemic countries. Keywords: Malaria, antimalarial drugs, plasmodium.
抗疟疾药物化学研究进展
在经常发生疟疾传播的国家以及温带地区,疟疾仍然是一个重要的公共卫生问题,是一个重大的全球卫生问题,估计每年有5亿临床病例。疟疾是一种复杂的疾病,在世界不同地区的流行病学和临床表现差异很大。最流行和最危险的疟疾类型是由恶性疟原虫引起的。间日疟原虫在拉丁美洲、亚洲和大洋洲是疟疾的常见病因,但在非洲并非如此。疟疾疟原虫和卵形疟原虫较不常见。抗疟药有三种不同的使用方式:预防、治疗恶性疟疾和治疗非恶性疟疾。预防性抗疟药几乎只由来自发达国家的旅行者在访问疟疾流行国家时使用。关键词:疟疾;抗疟药物;疟原虫;
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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