Profiling Human Coronavirus Genomic Data Obtained from Patients in Belarus

M. Sprindzuk, A. S. Vladyko, L. Titov, V. Bernik
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Abstract

The new coronavirus infection has caused the death and injury of millions of people and animals. The pandemic has shown the shortcomings of the health care systems of even the most economically developed countries. Genomics and bioinformatics provide an opportunity to obtain, study and analyze the genomic texts of microbes, coronaviruses in particular. The article presents the results of the analysis of SARS-CoV-2 genomes from patients in Belarus and (for comparison) in Russia. Genomic profiling was performed to identify and statistically analyze clusters and lines of transmission of the new coronavirus infection, in accordance with the proposed classifications of COVID-19 clades. The information on the assessment of the quality of the initial data are reported, the visualization of the results obtained is made and graphically presented. The dominant clades-clusters in Belarus and Russia are B.1 (“Basel cluster”) and B.1.1. Both have European-British geographical distribution
从白俄罗斯患者获得的人类冠状病毒基因组数据分析
新型冠状病毒感染已造成数百万人和动物死亡和受伤。这次大流行表明,即使是经济最发达的国家,其卫生保健系统也存在缺陷。基因组学和生物信息学为获取、研究和分析微生物,特别是冠状病毒的基因组文本提供了机会。本文介绍了白俄罗斯和俄罗斯患者(用于比较)的SARS-CoV-2基因组分析结果。根据提出的COVID-19进化支分类,进行基因组分析,以确定和统计分析新型冠状病毒感染的聚集性和传播途径。报告了对初始数据质量的评估信息,对获得的结果进行了可视化并以图形方式呈现。白俄罗斯和俄罗斯的主要分支群是B.1(“巴塞尔集群”)和B.1.1。两者都有欧洲-英国的地理分布
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