EFFICACY AND SAFETY OF PRIMARY CLOSURE OF COMMON BILE DUCT FOLLOWING LAPAROSCOPIC CHOLEDOCHOLITHOTOMY

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Abstract

Following surgical intervention for symptomatic cholelithiasis, approximately 10 to 15 percent of patients are diagnosed with choledocholithiasis, characterized by the presence of stones in CBD. Several surgeons perform open CBD exploration with primary duct closure. However, few surgeons perform duct closure laparoscopically due to technical difficulties and concerns about missed stones and postoperative complications. Thus, we evaluated the efficacy and safety of the primary closure of the common bile duct following laparoscopic choledocholithotomy. In this prospective observational study, 62 patients with CBD stones were confirmed pre-operatively by abdominal ultrasonography and/or magnetic resonance cholangiopancreatography (MRCP). CBD radiological findings and demographics were noted. Details on the intraoperative technique, overall operating time, and post-operative complications were observed. Patients were followed for one month, and post-operative data were collected and analysed. Most of the enrolled patients were female (69.35%), aged 41-50 (37.10%), and had abdominal pain (82.25%). 64.52% had multiple stones in the CBD of the calibre of 8–10 millimetres (40.32%). 94.52±21.58 mins was the mean operative time. CBD clearance was noted in 96.77% of cases. In most cases, intraoperative bleeding was 51–100 ml. Laparoscopic primary closure was performed in 96.77% of patients. On days 3 and 7, 9.68% and 6.45% of patients had bile leakage, respectively. The removal of abdominal drains varied significantly between cases. During the follow-up, two patients with bile leaks and jaundice after surgery were found to have retained stones and underwent post-operative ERCP without additional complications. The primary closure after LCBDE is considered a safe and effective alternative to T-tube drainage with an acceptable short-term outcome.
腹腔镜胆总管取石术后一期闭合胆总管的疗效和安全性
在对症状性胆石症进行手术干预后,大约10%至15%的患者被诊断为胆总管结石,其特征是CBD中存在结石。一些外科医生在初级管道封闭的情况下进行开放的CBD探查。然而,由于技术上的困难以及对遗漏结石和术后并发症的担忧,很少有外科医生在腹腔镜下进行导管闭合。因此,我们评估了腹腔镜胆总管取石术后一期关闭胆总管的有效性和安全性。在这项前瞻性观察研究中,62例CBD结石患者术前通过腹部超声和/或磁共振胆管造影(MRCP)确诊。记录了CBD放射学结果和人口统计学特征。观察术中技术、总手术时间及术后并发症。随访1个月,收集术后资料并进行分析。大多数患者为女性(69.35%),年龄41-50岁(37.10%),腹痛(82.25%)。64.52%(40.32%)在CBD有多颗直径为8-10毫米的结石。平均手术时间94.52±21.58 min。96.77%的病例中CBD清除。多数病例术中出血51 ~ 100 ml。96.77%的患者行腹腔镜一期缝合。第3天和第7天发生胆漏的比例分别为9.68%和6.45%。腹部引流管的清除在不同病例之间有显著差异。随访期间,2例术后胆漏及黄疸患者发现结石残留,术后行ERCP,无其他并发症。LCBDE后的初次闭合被认为是t管引流的一种安全有效的替代方法,具有可接受的短期结果。
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