Correlation of Bovine Dairy Igf-1 And the Neoplasia Development

Abstract

Cow's milk and its derivatives are among the most consumed foods in the world being part of the daily diet of several people. However, its consumption is linked to factors that were associated with neoplastic development, such as IGF-1. IGF-1 acts by stimulating growth effects on most cells of the body via the IGF1R receptor. In this context, this work aimed to investigate studies that correlate these variables: IGF-1, cow's milk, and neoplasias. The results showed that IGF-1 in cow's milk may increase serum IGF-1 levels in humans from milk consumption. Also, we have shown it that some supplements such as choline and casein do not alter the amount of IGF-1, but when the cow undergoes recombinant bovine somatotropin treatment, there is a significant increase in circulating IGF-1. However, further studies are needed to explain the cause-and-effect relationship noted in this study.