In Vitro Anthelmintic Effect of some Medicinal Plants against Haemonchus Contortus

Abstract

The study was undertaken to determine the anthelmintic activity of eight medicinal plants against adult and larvae (L3) of Haemonchus contortus during July to November, 2013. In vitro adulticidal and larvicidal activity were screened by preparing aqueous and methanol extract of some plants at 1%, 5% and 10% concentration with respect to control by PBS. The results revealed that neem showed best effect within 3 hour at 5% concentration (100%) and 10% concentration (100%) with methanol extract on adult Haemonchus. Rest of the ingredient showed their efficacy after 3 hours. Methanol extracts showed better effect than aqueous extracts. In case of L3 stage larvae, the highest efficacy was observed at 10% concentration in neem (100%) and korolla fruits(100%), followed by korolla leaves (80%), sharna lata (80%), lazzabati (60%) less than 3 hours. It is concluded that neem, korolla, sharna lata and lazzabati extract give a better approach against Haemonchus contortus and can be used against the treatment of haemonchosis in goat as an alternative of patent drug. So, further studies are required to find out the active ingredient of pharmacological and toxicological assessment and determine the recommended doses in goat.