Uwaga problem – wirus onkogenny HPV a nowotwory jamy ustnej i gardła

Agnieszka Kwaśniewska, Aleksandra Wawrzeńczyk, Katarzyna Brus-Sawczuk, Izabela Strużycka
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Abstract

Current epidemiological and molecular research has confirmed that HPV (human papillomavirus) infection is strongly associated with malignant tumors of the mouth and throat. HPV infection is currently considered to be one of the main causes of the growing incidence of squamous cell carcinoma in the oropharynx and oral cavity, in particular among populations of developed countries. HPV-positive cancers are characterized by a different from non-viral clinical image, epidemiology, risk factors and treatment protocols. Therefore, it deserves special attention and separate treatment. In recent years, there has been a significant increase in the incidence of HPV-positive carcinomas in the world, especially in the group of patients under 50 years of age. All of these factors lead to the conclusion, that redefinition of risk groups for cancer of this area and updating of protocols and prophylaxis is needed. Younger patients should be provided with oral cancer prevention programs, it is also advisable to promote vaccinations. The article describes current epidemiological status and the state of knowledge about HPV positive cancers of mouth and throat region.
目前的流行病学和分子研究证实,HPV(人乳头瘤病毒)感染与口腔和咽喉恶性肿瘤密切相关。HPV感染目前被认为是口咽和口腔鳞状细胞癌发病率不断上升的主要原因之一,特别是在发达国家的人群中。hpv阳性癌症的特点是不同于非病毒的临床形象,流行病学,危险因素和治疗方案。因此,它值得特别注意和单独处理。近年来,世界范围内hpv阳性癌的发病率显著增加,特别是在50岁以下的患者群体中。所有这些因素导致的结论是,需要重新定义该地区的癌症风险群体并更新方案和预防措施。应为年轻患者提供口腔癌预防方案,也建议提倡接种疫苗。本文介绍了目前的流行病学状况和对口腔和咽喉地区HPV阳性癌症的认识状况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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