New Trends in the Treatment of Grade II Furcation Defects by Using Second Generation Platelet Concentrates

Juan Pablo Pava Lozano, Manuel Alejandro Sabogal, Dayana Andrea Mora, Yuly Constanza Ortiz, Juan Pablo, Hinojosa, David Gutierrez, Ana Luisa Munoz
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Abstract

The furcation defect is defined as the pathological reabsorption of interadicular bone that occurs in multi-rooted and bi-rooted teeth in advanced stages of periodontal disease, it represents a great challenge for dentists and specialists when treating them, due to their different anatomical variations such as: root trunk, furcation opening, root relationship, interdental and interadicular morphologic features, the interadicular separation and the angle of root distance, that can interfere in the response to treatment. Some surgical strategies to cover furcation defects and exposed roots include free gingival grafts, pedicle flaps, sub epithelial connective tissue grafts, and application of different biomaterial-based grafts. We present a Case report of a 49 year-old patient who was diagnosed with grade II furcation defects on teeth 46 and 47, which were treated with Platelet- Rich Fibrin (PRF) is an autograft obtained from a blood sample of the patient undergoing processing in a centrifuge machine plus a coronal displacement flap surgical technique. A mucoperiosteal partial superficial thickness flap was lifted up from affected teeth and PRF was obtained from a patient blood sample (10mL) in a glass tube without anticoagulant, which was immediately processed on centrifuge machine. The flap was repositioned to coronal level beyond the cement enamel line with 2 PRF membranes placed on the root surfaces and sutured. Morphometric, tomography and clinical measurement was performed 6 months after the procedure to analyze the interadicular molar zones. The surgery showed presence of hard and soft tissues evaluated clinically and tomographically with a significant coverage of p <0.05 in the fornix zones of the molars. On the interadicular area morphometric values shows that tooth 46 there was a decrease (0.0005) of -1.127 (2.104 ± 0.06 vs 0.977 ± 0.07) of defect and tooth 47 (0.0047) of -0.850 (1.891 ± 0.04) vs 1.041 ± 0.05) CONCLUSION Use of CDF together with PRF can be considered as a treatment option because it achieves a ostensibly osteoconductive, biocompatible function and reduces patient recovery time improving the prognosis of established defects.
第二代血小板浓缩物治疗ⅱ级功能缺陷的新进展
分叉缺损被定义为牙周病晚期多根和双根牙齿中发生的根间骨的病理性重吸收,由于它们的不同解剖变异,因此在治疗时对牙医和专家来说是一个巨大的挑战,例如:根干、分岔开度、根间关系、牙间和根间形态特征、根间分离和根距角度等都会影响对治疗的反应。修复分叉缺损和暴露根的一些手术策略包括游离牙龈移植、蒂瓣、上皮下结缔组织移植以及不同生物材料移植的应用。我们报告了一名49岁患者的病例报告,该患者被诊断为46号和47号牙齿上的II级分叉缺陷,并使用富血小板纤维蛋白(PRF)治疗。富血小板纤维蛋白(PRF)是从患者的血液样本中获得的自体移植物,经过离心机处理和冠状移位皮瓣手术技术。从患牙上取下粘骨膜部分浅表厚度皮瓣,在无抗凝剂的玻璃管中从患者血液样本(10mL)中提取PRF,立即在离心机上处理。将皮瓣重新定位至冠状水平,超过水泥牙釉质线,在根表面放置2个prf膜并缝合。手术后6个月进行形态测量、断层扫描和临床测量,分析齿根间磨牙区。手术显示有硬软组织存在,临床和断层扫描评估,在磨牙穹窿区显著覆盖p <0.05。牙根间区形态测量值显示,46号牙缺损减少了-1.127(2.104±0.06 vs 0.977±0.07)(0.0005),47号牙缺损减少了-0.850(1.891±0.04)(0.0047)(1.041±0.05)(0.0005)。结论CDF与PRF联合使用可达到表面骨传导和生物相容性,缩短患者恢复时间,改善已建立缺损的预后,可作为一种治疗选择。
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