Assessment of the Availability and Utilization of Medicines Used for Preventing and Treating Malaria in Public Health Facilities in Jimma Town, Southwest Ethiopia

A. Bekele
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Abstract

Malaria remains a major global public health and development challenge. It caused 216 million cases and 655,000 deaths worldwide in 2010, of which 81% of the cases and 91% of the deaths were from sub-Saharan Africa [1]. In Ethiopia, malaria also remains one of the most public health problems despite considerable effort made to control it [2-4]. Approximately 75% of the land mass where 68% of the total population lives is malarious [2]. The Federal democratic Republic of Ethiopia Ministry of Health estimated that there are more than 5 million clinical cases and thousands of deaths due to malaria each year [2]. However, the epidemiological pattern of the disease varies from place to place and even from time to time [5-7]. About 1 million confirmed clinical cases and 1,581 deaths were officially reported due to malaria in 2010. Malaria poses a significant impediment to social and economic development and the disease was responsible for the greatest economic burden upon most of the countries in the southern part of the Sahara. In 1995, the average gross domestic product (GDP) in malarias countries was five-fold lower compared to non-malaria countries [8]. The economic loss caused by malaria in Africa in 1995 was estimated at 800 million U.S dollars. By 1997 this figure has risen to USD 2 billion, an enormous health and socioeconomic burden to an already poor continent [9]. The burden of malaria has been intensified by the appearance of chloroquine-resistant plasmodium falciparum, which arouse in south East Asia and was first documented in east Africa in 1979. Since then, there have been reports of chloroquine resistance in most countries in Africa, with especially high resistance in east Africa. In addition, Abstract
评估埃塞俄比亚西南部吉马镇公共卫生设施中用于预防和治疗疟疾的药物的供应和利用情况
疟疾仍然是一项重大的全球公共卫生和发展挑战。2010年,它在全球造成2.16亿例病例和65.5万人死亡,其中81%的病例和91%的死亡发生在撒哈拉以南非洲[1]。在埃塞俄比亚,尽管为控制疟疾作出了相当大的努力,但疟疾仍然是最严重的公共卫生问题之一[2-4]。在占总人口68%的土地上,大约75%的土地存在疟疾[2]。埃塞俄比亚联邦民主共和国卫生部估计,每年有500多万疟疾临床病例和数千人死亡[2]。然而,该病的流行病学模式因地而异,甚至随时间而异[5-7]。2010年,官方报告了约100万疟疾确诊临床病例和1 581人死亡。疟疾对社会和经济发展构成重大障碍,这种疾病是撒哈拉南部大多数国家最大的经济负担。1995年,疟疾国家的平均国内生产总值(GDP)比非疟疾国家低5倍[8]。据估计,1995年非洲因疟疾造成的经济损失达8亿美元。到1997年,这一数字已上升到20亿美元,这对一个已经贫穷的大陆来说是一个巨大的健康和社会经济负担[9]。疟疾的负担因氯喹耐药恶性疟原虫的出现而加剧,该疟原虫在东南亚引起,并于1979年在东非首次记录。从那时起,非洲大多数国家都有氯喹耐药性的报告,东非的耐药性特别高。此外,摘要
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