Shweta Singh, Umesh Kumar Singh, S. Krishna, Abhishek Bannerjee, P. Rai, Shashank Srivastava
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引用次数: 0
Abstract
Xerostomia is a complicated condition that is becoming more prevalent in the elderly population due to several causes ranging from developmental to iatrogenic. Pharmacological treatment improves the symptoms but increases the adverse effects of the latter and worsens the situation again. Keeping this in mind non-pharmacological interventions are currently used or under supervision to bypass the complications of pharmacological treatment. This article aims to review the prevalence incidence causes signssymptoms and most importantly the success rate of non-pharmacological interventions. Articles in PubMed Cochrane database and Web of Science were analysed till date to establish the effectiveness of different modalities such as acupuncture electrostimulation hyperbaric oxygen HBO therapy and low-level laser therapy LLLT etc. Newer treatment modalities such as gene therapy and stem cell therapy are under trial. This paper provides a broad idea of the different non-pharmacological interventions currently used and our newer future for treating dry mouth.
口干症是一种复杂的疾病,由于发育和医源性的多种原因,在老年人中变得越来越普遍。药物治疗改善了症状,但增加了后者的不良反应,使情况再次恶化。记住这一点,目前使用非药物干预或在监督下绕过药物治疗的并发症。本文旨在回顾患病率、发病率、病因、症状和最重要的非药物干预的成功率。我们分析了PubMed Cochrane数据库和Web of Science中的文章,以确定针灸、电刺激、高压氧、高压氧治疗和低水平激光治疗等不同治疗方式的有效性。新的治疗方式,如基因治疗和干细胞治疗正在试验中。本文提供了不同的非药物干预目前使用和我们的新未来治疗口干的一个广泛的想法。