Level of High-density Lipoprotein (HDL) and Triglycerides (TG) Predict Covid-19 Severity: The Systematic Review

Abstract

Background: Lipids have many functions that are indispensable in lung biology and the pathophysiology of viral infections. Methods: Systematic review with data sources derived from internet literature in the form of research results, both on Cochrane, Pub Med, Google scholar, and other journal databases. Researchers searched for the keywords "High-Density Lipoprotein (HDL)" or "High-Density Lipoprotein (HDL)"; "Triglycerides (TG)" or "Triglycerides (TG)"; "Predict Covid-19 Severity" or "COVID-19 Severity". The research included in this article is a study that focuses on the severity of Covid-19 based on HDL and TG levels. Results: Searching the Pub med journal database, we found only one journal that discussed the relationship between HDL and TG on the severity of Covid-19. A Google scholar search shows four studies that are relevant to this study. Conclusion: Low HDL levels and high triglyceride levels may be associated with longer hospital stays, increased inflammatory markers, need for ICU and mechanical ventilation, and poorer prognosis.