E. VERMICULARIS – PROSPECTS FOR FUTURE RESEARCH

E. Kaneva, R. Harizanov, N. Tsvetkova, Iskren Kaftanjiev, R. Borisova, A. Ivanova, M. Videnova, Desislava Velcheva, I. Alexiev, Reneta Dimitrova, M. Pavlova, E. Aleksandrova
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Abstract

Enterobius vermicularis is an intestinal parasite with a cosmopolitan distribution and the disease which causes (enterobiasis) is one of the most common helminth infection worldwide. According to literature data it affects nearly 1 billion people and is found in various socio-economic groups. Everyone is susceptible to infection, but children are more often affected than adults due to their poorly developed hygiene habits. Patients with enterobiasis are often reinfected which together with the high endurance of the pinworm eggs in the environment contributes to the difficult control of the disease. In recent decades, a number of studies have been conducted on the genotypic characteristics of the nematode, including sequencing, which accumulates data on phylogenetic varieties of the species to improve the diagnosis and control of this infection in humans.The available data reveal influence of E. vermicularis on the local immunity of intestinal mucosa in infected individuals, but these data are scarce and contradictory and do not clarify the significance of this influence on the clinical manifestations of the disease. Additional studies are needed to define the relationship of this effect with the clinical symptoms of the disease.
蛭形线虫——未来研究展望
蛭状肠虫是一种世界性的肠道寄生虫,其病因是世界范围内最常见的寄生虫感染之一。根据文献数据,它影响着近10亿人,存在于不同的社会经济群体中。每个人都容易受到感染,但由于儿童的卫生习惯不佳,他们比成年人更容易受到感染。蛲虫病患者经常发生再感染,再加上蛲虫卵在环境中的高耐久性,使得该病难以控制。近几十年来,人们对线虫的基因型特征进行了大量研究,包括测序,从而积累了该物种的系统发育变异数据,以提高对人类感染的诊断和控制。现有资料揭示了蛭状芽胞杆菌对感染个体肠道黏膜局部免疫的影响,但这些资料缺乏且相互矛盾,没有阐明这种影响对疾病临床表现的意义。需要进一步的研究来确定这种效应与该病临床症状的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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