Efficacy of Three Desensitizing Agents to Reduce Cervical Dentin Hypersensitivity: A Randomized Clinical Trial

Shikha Bantawa, M. Vikram, Navin Agrawal, Vimmi Singh, Ashok Ayer, A. Rai, Sita Shrestha, Santosh Kumari Agarwal
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Abstract

Introduction: Dentin hypersensitivity (DH) is a commonly encountered dental complaint, management of which is often challenging to dentists. It occurs when dentinal tubules are patent both at the pulpal and the oral surface. It is widely accepted that DH affects function and quality of life. Thus, it is necessary for dentists to manage it properly. Objective: The objective of this study was to assess the efficacy of VivaSens and Propolis in comparison to Gluma in reducing cervical dentin hypersensitivity. Methods: A randomized clinical trial, double-blinded, parallel-group study was conducted among forty-five patients. They were randomly allocated into three different groups (n=15): Gluma (positive control), VivaSens, and Propolis. Tactile and evaporative methods were used to assess pain using the Numeric Pain Rating Scale (NPRS) in patients with cervical abrasion, with a complaint of dentin hypersensitivity. Pain score was recorded preoperatively, immediately after application, at one week and one month postoperatively. Data were analyzed using SPSS version 11.5 and Microsoft Excel version 2010. Mean NPRS scores were calculated. Results: All three desensitizing agents significantly reduced DH scores from baseline to all subsequent follow-ups (p<0.001). Kruskal–Wallis test elicited no significant differences in the mean difference in DH scores among positive control and test groups for both stimuli at all-time intervals (p < 0.05). Conclusions: Gluma, VivaSens, and Propolis desensitizing agents were effective in relieving cervical DH. No statistically significant difference was found in relieving DH among the agents in all subsequent follow-ups.
三种脱敏剂降低颈牙本质过敏的疗效:一项随机临床试验
牙本质过敏症(DH)是一种常见的牙科疾病,其管理往往是牙医的挑战。当牙髓和口腔表面的牙本质小管都通畅时,就会发生这种情况。人们普遍认为DH影响功能和生活质量。因此,牙医有必要对其进行妥善管理。目的:本研究的目的是评估VivaSens和蜂胶在减少颈牙本质过敏方面的疗效,并与Gluma进行比较。方法:对45例患者进行随机临床试验、双盲、平行组研究。他们被随机分为三个不同的组(n=15): Gluma(阳性对照),VivaSens和蜂胶。采用数值疼痛评定量表(NPRS),采用触觉法和蒸发法对主诉牙本质过敏的颈椎磨损患者进行疼痛评定。术前、即刻、术后1周、1个月分别记录疼痛评分。数据分析采用SPSS 11.5版和Microsoft Excel 2010版。计算NPRS平均得分。结果:从基线到所有后续随访,所有三种脱敏剂均显著降低DH评分(p<0.001)。经Kruskal-Wallis检验,两种刺激在时间间隔内阳性对照组和试验组DH评分的平均差异无显著性差异(p < 0.05)。结论:Gluma、VivaSens、蜂胶脱敏剂均能有效缓解宫颈DH。在所有后续随访中,各药物缓解DH的效果均无统计学差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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