Deciphering of Anthelmintic Potential of Annona squamosa Leaf: Molecular Mechanistic

Abstract

Herbal treatments have historically been utilized to treat various human diseases. To find a single ingredient that could be the basis for creating new therapeutically effective products, researchers studied herbal medicines. Annona squamosa Linn has anti-inflammatory, hepatoprotective, anti-diabetic, cytotoxic, gene-toxic, and anticancer properties. The primary active components of A. squamosa leaves, flavonoids, have been utilised to treat a variety of human ailments. Quercetin and rutin, two flavonoids, have been shown to have anticancer, antiviral, anti-inflammatory, and heart disease preventive properties. In the present study in -vivo and in -silico evaluation of anthelmintic potential of Annona squamosa leaf methanolic extract was carried out. Further proposed mechanism of Anthelmintic efficacy of Annona squamosa leaf was determined by molecular docking.