Evaluation Of The Results Of Cordocentesis; 9 Years Experience

Abstract

Objective: To evaluate of results of cordosentesis in an University Clinic. Methods: Adequate amount of cord blood was taken from 96.9% of the cases, the successful culture rate was 99.2%. In seven cases the procedure was repeated as the culture was unsuccessful in two of them and maternal contamination was observed in five of them. There was no fetal loss among the 251 cordocentesis cases, but it must be taken into account that 62.2% of these patients were referred to our clinic so that their pregnancy outcomes could not be obtained. The most common complications were intraamniotic bleeding in 6.8% and transient fetal bradycardia in 6.3% of the cases. According to cytogenetic evaluation reports, chromosomal abnormality was detected in 13 cases (5.17%). One case with short femur had a karyotype of 47,XX,t(8;14) (p22;q21),+der(14)(8;14) and one case with single umblical artery having a karyotype of 46,XX,del(3)(p25pter) was described for the first time in the literature. Results: Data including the indications, cytogenetic results and complications was obtained from 251 pregnancies who underwent cordocentesis in a University clinic. Conclusion: Cordocentesis is an invasive prenatal diagnostic and therapeutic procedure with high accuracy and safety if it is carried out by highly skilled physicians and when optimal culture conditions are provided.