The Transfigured Ingot-Gastrointestinal Stromal Tumour

Abstract

Gastrointestinal stromal tumour is a frequently discerned, mesenchymal neoplasm occurring within gastrointestinal tract. Predominantly incriminating gastric region, tumefaction arises from interstitial cells of Cajal which constitute myenteric plexus situated within muscularis propria. Previously designated as gastrointestinal smooth muscle tumour, gastrointestinal autonomic nerve tumour, leiomyoblastoma, smooth muscle tumour of uncertain malignant potential or gastrointestinal pacemaker cell tumour, gastrointestinal stromal tumour may exhibit malignant biological behaviour [1,2]. Of obscure aetiology, majority of neoplasms are sporadic. However, few familial neoplasms may occur. Chromosomal mutations of KIT and PDGFRA genes are singularly associated with the tumour. Neoplasm may be discovered incidentally during various imaging or endoscopic procedures of gastrointestinal tract [1,2].