Acetone measurements in the exhaled air by the cavity ring-down spectrometry

G. Revalde, K. Grundsteins, A. Abola
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Abstract

Our work is focused to develop sensitive optical diagnostic methods for the detection of Volatile Organic Compounds in the breath. For the breath measurements, we have built a cavity ring-down spectrometer, operated in the UV region. The system was tested and calibrated using a KinTek automated permeation tube system with nitrogen as a carrier gas, as well as self- prepared acetone mixtures in air with known concentrations. In this paper, we present results of the measurements of acetone concentration in the breath for the test group of randomly selected 40 people in the age group over 50. We observed the values of acetone concentration in the breath in the range from 0,1 – 80 ppm, with a median 7,1 ppm. The experiments showed that the limits of detection for acetone with the cavity ring-down system are several tens of ppb.
用空腔衰荡光谱法测定呼出空气中的丙酮
我们的工作重点是开发灵敏的光学诊断方法来检测呼吸中的挥发性有机化合物。对于呼吸测量,我们已经建立了一个腔衰荡光谱仪,在紫外线区域运行。该系统使用KinTek自动渗透管系统进行测试和校准,以氮气为载气,以及在已知浓度的空气中自行制备的丙酮混合物。在这篇论文中,我们提出了在50岁以上的年龄组中随机选择40人的试验组呼气中丙酮浓度的测量结果。我们观察到呼出气体中的丙酮浓度在0.1 - 80ppm范围内,中位数为7.1 ppm。实验表明,该空腔衰荡系统对丙酮的检出限为几十ppb。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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