SURGICAL TREATMENT OF INFECTIOUS ENDOCARDITIS

A. Shonbin, D. Bystrov, Boris O. Afonin, Roman O. Sorokin
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Abstract

Infectious endocarditis is one of extremely dangerous diseases. Despite the opportunities of modern medicine, hospital mortality in infectious endocarditis remains high. Most patients are operated on for urgent and emergency indications. the article presents 11 years of experience in surgical treatment of infectious endocarditis at the State Budgetary Healthcare Institution JSC "PGKB named after E.E. Volosevich" in the town of Arkhangelsk. the study included 169 patients with infectious endocarditis, verified based on the presence of criteria corresponding to the modified Duke criteria. Infectious endocarditis of native valves (group I) was compared to prosthetic endocarditis (group II). the operative risk according to the EuroScore I, II and STS scales was significantly higher in the group of patients with prosthetic infectious endocarditis (p < 0.001). Para-valve destructive changes were more common (p = 0.05) in the group of prosthetic infectious endocarditis. There were no statistically significant differences in the localization of infectious endocarditis (p > 0.05), however, multiple valve lesions were more often observed in infectious endocarditis of native valves (p = 0.05). a complicated postoperative period was detected in 41.9% of patients of group I and in 71.4% of group II (p = 0.05). Hospital mortality in group I was 3.4%, in group II – 9.5% (p < 0.001). the main cause of death in the postoperative period was acute cardiovascular insufficiency. Despite the fact that hospital mortality in the surgical treatment of active infectious endocarditis continues to be high, surgical intervention in active infectious endocarditis is the only effective method of treatment.
感染性心内膜炎的外科治疗
感染性心内膜炎是一种非常危险的疾病。尽管有现代医学的机会,感染性心内膜炎的住院死亡率仍然很高。大多数病人因紧急和紧急指征而接受手术。文章介绍了在阿尔汉格尔斯克镇的国家预算医疗机构JSC“以E.E. Volosevich命名的PGKB”11年感染性心内膜炎手术治疗的经验。该研究纳入了169例感染性心内膜炎患者,并根据修改后的Duke标准进行了验证。将原生瓣膜感染性心内膜炎(I组)与假体心内膜炎(II组)进行比较,假体感染性心内膜炎患者的EuroScore I、II和STS评分的手术风险显著高于假体感染性心内膜炎组(p < 0.001)。假体感染性心内膜炎组瓣膜旁破坏性改变更为常见(p = 0.05)。感染性心内膜炎的定位差异无统计学意义(p < 0.05),而原生瓣膜感染性心内膜炎多见于多发瓣膜病变(p < 0.05)。术后并发症发生率分别为41.9%和71.4% (p = 0.05)。I组住院死亡率为3.4%,II组为9.5% (p < 0.001)。术后死亡的主要原因是急性心血管功能不全。尽管手术治疗活动性感染性心内膜炎的住院死亡率仍然很高,但手术干预是活动性感染性心内膜炎唯一有效的治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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