Discriminant models of the possibility of occurrence and course of psoriasis in men of the general group and different somatotypes depending on the characteristics of anthropo-somatotypological indicators

Al-Qaraleh Obadeh Bassam Abdel-Rahman, S. Dmytrenko, V. Kyrychenko, G. V. Datsenko, V. Gunas
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引用次数: 2

Abstract

Significant prevalence and multifactorial occurrence of psoriasis are the main reasons why this disease has been studied for years by scientists in the field of dermatology. Finding tools to predict the occurrence and severity of this disease is one of the key unrealized areas of modern medicine in the field of skin diseases. The purpose of the study is to build and analyze discriminant models of the possibility and features of psoriasis course in Ukrainian men without and taking into account the somatotype, depending on the structure and size of the body. Anthropometric and somatotypological examination of 82 practically healthy and 100 patients with mild and severe psoriasis was performed. Construction of discriminant models of the possibility of occurrence and features of psoriasis depending on anthropo-somatotypological indicators is performed in the license package “Statistica 5.5”. It was found that men of the general group and representatives of the mesomorphic somatotype can reliably interpret the obtained classification indicators both between healthy and patients with psoriasis of different course, and between men with psoriasis of mild and severe course (correctness 84.1% of cases, statistics Wilks’ Lambda=0.074, р<0.001 in the general group, correctness 83.6% of cases, statistics Wilks’ Lambda=0.077, р<0.001 in mesomorphic somatotype). In men of endo-mesomorphic somatotype, a reliable interpretation of the obtained classification indicators is possible only between healthy and psoriatic men (correctness 84.6%, statistics Wilks’ Lambda=0.027, р<0.001). Discriminant models in men of the general group include body diameters and SFT (44.4% each) and the fat component of body weight (11.1% each); in men of mesomorphic somatotype – body diameters (57.1%), SFT (28.6%) and body surface area (14.3%); in men of endo-mesomorphic somatotype – body diameters (60.0%) and SFT on the thigh and the height of the finger anthropometric point (20.0% each). The greatest contribution to discrimination in men of the general group and representatives of the mesomorphic somatotype is made by shoulder width, and in men of endo-mesomorphic somatotype – shoulder width, interspinous and intercristal distances. The results obtained, especially in the division of men into somatotypes, indicate a high genetic predisposition to psoriasis.
基于人-体型指标特征的普通人群和不同体型男性银屑病发生和病程的判别模型
银屑病的显著患病率和多因素发生是皮肤科科学家多年来研究此病的主要原因。寻找工具来预测这种疾病的发生和严重程度是现代医学在皮肤病领域未实现的关键领域之一。该研究的目的是建立和分析乌克兰男性银屑病病程的可能性和特征的判别模型,不考虑身体类型,取决于身体的结构和大小。本文对82例实际健康患者和100例轻、重度牛皮癣患者进行了人体测量学和躯体分型检查。在“Statistica 5.5”许可包中,根据人类-躯体类型指标构建牛皮癣发生可能性和特征的判别模型。结果发现,普通组和中形态躯体型男性代表均能可靠地解释所获得的分类指标,无论是健康人与不同病程银屑病患者之间,还是轻度病程银屑病男性与重度病程银屑病男性之间(普通组的病例正确率为84.1%,统计学Wilks’Lambda=0.074, <0.001;中形态躯体型的病例正确率为83.6%,统计学Wilks’Lambda=0.077,统计学Wilks’Lambda=0.077, <0.001)。在内中形态躯体型男性中,获得的分类指标只有在健康男性和银屑病男性之间才有可能得到可靠的解释(正确率为84.6%,统计数据Wilks’Lambda=0.027, r <0.001)。普通组男性的判别模型包括体径和SFT(各占44.4%)和体重的脂肪成分(各占11.1%);中胚型男性:体径(57.1%)、SFT(28.6%)和体表面积(14.3%);内中形态型男性:体径(60.0%)、大腿SFT和手指人体测量点高度(20.0%)。在一般人群和中胚型男性中,最大的歧视因素是肩宽,而在内胚型男性中,最大的歧视因素是肩宽、棘间和嵴间距离。获得的结果,特别是在将男性划分为不同的体型时,表明患牛皮癣的遗传易感性很高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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