Calcium Alginate Polysaccharide Dressing as an Accelerated Treatment for Burn Wound Healing

Abstract

Patients with burn injuries suffer from pain and an inflammatory response; however, treatment methods are still not satisfactory and remain challenging. Due to the long stage of burn wound rehabilitation, which contributes to the long-term sensory problems, an effective treatment must begin at the outset of burn wound care. The functionalized wound dressing is expected to be a great treatment strategy over the commercialization wound dressing products and engineered skin substi-tutes nowadays. Some studies revealed the use of calcium alginate polysaccharide (CAPS) as an “ active ” dressing due to its calcium richness for wound healing and scar tissue formation. The outstanding outcome of CAPS dressing for severe burn injuries was indicated by natural wound healing and less scarring formation, minimum bacterial infection, cytokine enhancement regulation, and appropriate inflammatory response and pain regulation. These advantages affirmed the phyto-polysaccharide dressing as the next generation of wound dressing materials with highly desirable properties.