Discoid Lupus Erythematosus and Vitiligo

Abstract

Patients with autoimmune conditions are more likely than others to develop additional inflammatory or disimmunity affections. Both discoid lupus eryhtematosus (DLE) and vitiligo may associate with various other autoimmune disorders. Coexistence of DLE and vitiligo in the same patient have also been reported. Understanding of this rare pathological association remains unclear and diagnosis may appear challenging as depigmentation manifests in both diseases. Through the clinical, histological and immunochemical findings of a 38-year-old patient with simultaneous DLE and vitiligo, we discuss physiopathology, diagnosis and management of this unlikely association.