Study of efficacy of intravenous iron sucrose in patients with moderate iron deficiency anemia in pregnancy

Abstract

Introduction: Iron deficiency continues to be one of the most prevalent single nutrient deficiencies in the world. In the case of pregnant population, treatment of iron deficiency anemia efficiently would lead to a considerable reduction in the risk factors affecting maternal and fetal outcome. Materials and Methods: In this retrospective, case control study; the data of pregnant women who have received uniform dose of Intravenous and oral therapy for proven moderate iron deficiency anemia in the second trimester were studied for efficacy and safety parameters. The hemoglobin levels before and after initiating treatment in both groups were compared. Results and Conclusions: Intravenous and oral; both the treatments were associated with increment in hemoglobin but this rise was significantly more in the intravenous group than in oral. Comparing participants with low pretreatment hemoglobin among both groups, participants in the intravenous group were better benefited than oral due to respective treatment. Further it is found that hemoglobin increment is inversely proportional to the pretreatment hemoglobin irrespective of route of administration. Also intravenous iron is better tolerated compared to oral iron. So it can be concluded that intravenous iron therapy is much effective in correcting iron deficiency anemia in pregnancy than oral iron therapy.