A computer model of intracranial dynamics

W. Thoman, S. Lampotang, D. Gravenstein, J. van der Aa
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引用次数: 4

Abstract

A software model of intracranial dynamics was developed using existing relationships between patient physiology and brain dynamics. The relationship between the physiologic parameters arterial partial pressure of oxygen (PaO/sub 2/), arterial partial pressure of carbon dioxide (PaCO/sub 2/), mean arterial blood pressure (MABP), temperature (T) and brain dynamics were obtained from literature and were coded into software using Borland C. This computer model was integrated with a full scale patient simulator which generated the physiological inputs to the brain model. This integration allows users of the patient simulator to see the effects of their clinical interventions on brain dynamics through a real-time display. The display outputs the following intracranial variables: cerebral blood flow (CBF), cerebral blood volume (CBV), cerebral metabolic rate (CMRO/sub 2/), cerebral perfusion pressure (CPP), and intracranial pressure (ICP). The ability to visualize intracranial events as they are affected by physiology is a useful tool for teaching and training students.
颅内动力学的计算机模型
利用患者生理和脑动力学之间的现有关系,开发了颅内动力学的软件模型。从文献中获取生理参数动脉血氧分压(PaO/sub 2/)、动脉血二氧化碳分压(PaCO/sub 2/)、平均动脉血压(MABP)、体温(T)与脑动力学之间的关系,并使用Borland c软件编码。该计算机模型与全尺寸患者模拟器集成,该模拟器生成脑模型的生理输入。这种集成允许患者模拟器的用户通过实时显示看到他们的临床干预对大脑动力学的影响。显示器输出以下颅内变量:脑血流量(CBF)、脑血容量(CBV)、脑代谢率(CMRO/sub 2/)、脑灌注压(CPP)、颅内压(ICP)。可视化颅内事件受生理影响的能力是教学和训练学生的有用工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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