In Vitro Anti Cancer Activity of Ethanolic Extract of Eclipta Alba (L.)

Y. Anil Kumar, K. Ravi Kumar, Y. Sirisha, B. Gopikrishna, S. Yashita raga
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引用次数: 2

Abstract

Cancer is a group of diseases involving uncontrolled and abnormal growth of cells with potential to invade (or) spread to other parts of body. The aim of present study is to evaluate the invitro anti cancer screening of ethanolic extract of whole plant of Eclipta alba against HL-60 cell lines by SRB (sulphorhodamine) assay, besides this property it has many other therapeutic uses. The plant with methanol is kept in closed vessel for seven days and the obtained extract is subjected to preliminary phytochemical analysis and in vitro anti cancer screening, these test reveals the presence of secondary metabolites and LD50 concentration of extract was >80 μg/ml respectively i.e) the extract can inhibit the growth of cancer cells rather than killing them. For killing the cancerous cells very high concentration of extract is required.
黄花醇提物体外抗癌活性研究
癌症是一组疾病,涉及细胞不受控制和异常生长,具有侵入(或)扩散到身体其他部位的潜力。本研究的目的是评价黄花全株乙醇提取物体外抗HL-60细胞株的SRB(硫代丹胺)筛选作用,以及其具有的多种治疗作用。将植物用甲醇密闭容器保存7天,得到的提取物进行初步的植物化学分析和体外抗癌筛选,这些测试表明,提取物的次级代谢物的存在和LD50浓度分别为bbb80 μg/ml,即提取物可以抑制癌细胞的生长而不是杀死癌细胞。为了杀死癌细胞,需要非常高浓度的提取物。
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