Green Synthesis of Mixed Metal Oxide (MnO, CuO, ZnO) Nanoparticles (NPs) using Rose Petal Extract: An investigation of their Antimicrobial and Antifungal Activities

S. S. Gillani, S. Khan, R. Nazir, A. Qurashi
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引用次数: 1

Abstract

In this study, mixed metal oxide (CuO, ZnO, and MnO) nanoparticles (NPs) were synthesized via the green process, which is considered to be simple, cost-effective, eco-friendly, and non-toxic. During the green synthesis method, rose petal extract was used as a reducing and capping agent, while salt solutions (CuCl2, MnCl2, and ZnSO4) were used for the bio-reduction of metal precursors, leading to the formation of mixed metal oxide (CuO, ZnO, MnO) NPs. UV-Visible and FTIR spectroscopy were used for the analysis of mixed metal oxide (CuO, ZnO, MnO) NPs. The results showed maximum absorbance of the mixed metal oxide in the range of 280 to 370 nm. The presence of particular peaks in FTIR verified the synthesis of mixed metal oxide nanoparticles. Subsequently, the antimicrobial and antifungal activities of mixed metal oxide (CuO, ZnO, MnO) NPs were tested by using the disc diffusion method and well diffusion method. Mixed metal oxide (CuO, ZnO, MnO) NPs displayed antimicrobial activity against Escherichia coli and antifungal activity against Candida albicans, Curvularia lunata, Aspergillus niger, and Trichophyton simii. Hence, these mixed metal oxide (CuO, ZnO, MnO) NPs can be effectively used in the pharmaceutical sector. Keywords: antifungal, antimicrobial, green synthesis, mixed metal oxides nanoparticles (MONPs), rose petals extracts Copyright (c) The Authors
玫瑰花瓣提取物绿色合成混合金属氧化物纳米颗粒(MnO, CuO, ZnO)的抑菌活性研究
在本研究中,通过绿色工艺合成了混合金属氧化物(CuO, ZnO和MnO)纳米颗粒(NPs),该工艺被认为是简单、经济、环保和无毒的。绿色合成方法采用玫瑰花瓣提取物作为还原封盖剂,盐溶液(CuCl2、MnCl2和ZnSO4)对金属前驱体进行生物还原,形成混合金属氧化物(CuO、ZnO、MnO) NPs。采用紫外可见光谱和红外光谱对混合金属氧化物(CuO、ZnO、MnO) NPs进行了分析。结果表明,混合金属氧化物的最大吸光度在280 ~ 370 nm范围内。红外光谱中出现的特殊峰证实了混合金属氧化物纳米颗粒的合成。随后,采用圆盘扩散法和孔扩散法检测了混合金属氧化物(CuO、ZnO、MnO) NPs的抑菌活性。混合金属氧化物(CuO, ZnO, MnO) NPs对大肠杆菌和白色念珠菌、月曲菌、黑曲霉和相似毛癣菌具有抗菌活性。因此,这些混合金属氧化物(CuO, ZnO, MnO) NPs可以有效地用于制药部门。关键词:抗真菌,抗菌,绿色合成,混合金属氧化物纳米颗粒(MONPs),玫瑰花瓣提取物
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