Carbon Nanotubes for Targeted Cancer Therapy

Abstract

The sections in this article are Introduction Cancer Conventional Cancer Chemotherapy versus Nanocarrier-Mediated Drug Delivery Challenges with Chemical Compounds as Therapeutic Agents Advantages of Nanocarriers as Drug-Delivery Vehicles Carbon Nanotubes as Drug-Delivery Vehicles Cellular Uptake of CNTs Functionalization of CNTs with Polyethylene Glycol Targeting of Cancers Passive Targeting Active Targeting Trafficking of Targeted Drug-Delivery Vehicles Targeted Cancer Therapy Employing CNTs and a Critique of Current Studies erbB Family Members Folate Receptor α Biotin Receptor Integrins Markers for Lymphomas or Leukemias Disialoganglioside (GD2) Summary and Future Perspective Acknowledgments Keywords: Carbon nanotubes; single-walled carbon nanotubes; multi-walled carbon nanotubes; cancer; targeting; PEGylation; drug delivery