A prospective study of comparison of analgesia and foetal outcome in term parturients with and without low dose combined spinal epidural labour analgesia

Nenavath Sudheer Kumar Naik, P. Khanapurkar
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Abstract

Background: Ideally pain relief with epidural techniques should be produced with minimum disturbance to the progress of labour or to sympathetic functions, sensory functions (proprioception) and motor functions of the CNS. Materials and Methods: This study was undertaken after obtaining approval from the Research and Ethics committee of the hospital. Written informed consent was obtained from all parturients. This study did not interfere with the normal obstetric management technique employed in this hospital. This is a prospective case control study. The study population included 120 pregnant women 60 of who were given labour analgesia-‘GROUP T’ and 60 of who underwent a delivery without labour analgesia-‘GROUP C’. Studied patients were ASA physical status I and II parturients with term singleton gestations and cephalic presentation who requested analgesia. When the patient was in active labor, achieving a cervical dilation of 3-4cm and requested analgesia, a combined spinal-epidural technique was used. Parturients were excluded who were unwilling, any contraindication to regional technique, history of local anesthetic allergy, psychological or neurological diseases. Results: There were no differences between the groups with respect to demographic and labor characteristics. Gestational age. Height and weight, Parity, cervical dilatation at which analgesia was instituted, were compared and no significant difference was obtained (p>0.05). Though a higher mean systolic and diastolic BP, pulse rate were seen in stage 2 in both groups, the vitals were significantly lower in Group T in both stage 1 and 2 when compared to Group C. Conclusion: Low dose’ labour analgesia is a safe technique for painless labour with no harmful effects on the mother or baby and it does not significantly affect the obstetric outcome.
低剂量脊髓硬膜外联合镇痛对足月产妇镇痛和胎儿结局的前瞻性研究
背景:理想情况下,硬膜外镇痛应尽量减少对分娩进程或交感神经功能、感觉功能(本体感觉)和中枢神经系统运动功能的干扰。材料与方法:本研究经医院研究与伦理委员会批准后进行。获得了所有产妇的书面知情同意。本研究并未干扰该医院采用的正常产科管理技术。这是一项前瞻性病例对照研究。研究人群包括120名孕妇,其中60名使用了分娩镇痛药(“T组”),60名未使用分娩镇痛药(“C组”)。研究的患者是ASA身体状态I和II的单胎妊娠足月头位孕妇,要求镇痛。当患者处于产程,宫颈扩张3-4cm并要求镇痛时,采用脊髓-硬膜外联合技术。排除不愿意、有区域技术禁忌症、有局麻过敏史、有心理或神经疾病的产妇。结果:两组在人口统计学和劳动特征方面没有差异。胎龄。比较身高、体重、胎次、宫颈扩张镇痛时间,差异无统计学意义(p>0.05)。虽然两组在第2期均有较高的平均收缩压和舒张压、脉搏率,但与c组相比,T组在第1期和第2期的生命体征明显较低。结论:低剂量分娩镇痛是一种安全的无痛分娩技术,对母亲或婴儿没有有害影响,对产科结局没有显著影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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