Hydrogels-Based Textile Materials for Treatment of First-Degree Burn Injuries

Abstract

Hydrogels based on collagen and xanthan have found various applications as drug delivery carriers. The main strategy is to combine the traditional perspective of using essential oils with polymeric hydrogels in order to develop a potential dressing that provides wound healing for first-degree burn injuries. In this regard, the present study is aimed to develop textile materials with potential for use in the treatment of first-degree burn injuries by approaching the hydrogels based on xanthan gum and collagen as polymeric matrix loaded with essential oils (cinnamon essential oil, tea tree essential oil), propolis (hydroglyceric extract or with content of colloidal silver) and drugs (chlorhexidine, ciprofloxacin). A total of six experimental variants of hydrogels were synthesized and then were applied by padding method on a plain weave textile structure from 100% cotton. The functionalized textile materials were characterized by morphological and antibacterial point of view. The textile materials treated materials with all synthesized hydrogels based on xanthan and collagen as polymeric matrices have antibacterial activity against S. aureus and E. coli test strains, the highest inhibition zone was provided by the samples loaded with ciprofloxacin (MUP3 and MUP4 code).