Successful Treatment of Ulcers with Honey-Based Topical Preparation: Five Case Reports

S. Nasrollahi
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Abstract

Background and objectives: Ulcers are a global public health problem in the world, and expensive wound dressings are not universally available. Most wound patients suffer injuries that can be treated conservatively. However, the ideal dressing for the wound has not been identified. The aim of the study was to evaluate the changes in physical and morphological properties due to topical application of honey ointment on diabetic foot ulcers or cutaneous wounds. Methods: Honey ointment contained 40% honey in the lanoline base. Five patients of either sex were selected. Site of the wound, shape, size, and margin were recorded on day 0 and observed during weeks 2-3, and also to the end of healing to record the progression of granulation, scar type, shape, size, and clinical symptoms. Results: There was significant improvement in the healing process as formulation possesses antibacterial, wound cleansing, and wound healing properties. All patients showed significant improvement after 2-3 weeks with honey ointment. Conclusion: a combination of honey and lanolin may be effective in the treatment of low to moderate wounds.
以蜂蜜为基础的局部制剂成功治疗溃疡:5例报告
背景和目的:溃疡是一个全球性的公共卫生问题,昂贵的伤口敷料并不是普遍可用的。大多数伤口患者所受的伤害可以保守治疗。然而,理想的伤口敷料尚未确定。该研究的目的是评估由于局部应用蜂蜜软膏在糖尿病足溃疡或皮肤伤口的物理和形态学特性的变化。方法:在羊毛油基中添加40%的蜂蜜。男女各选5名。在第0天记录创面部位、形状、大小和边缘,并在第2-3周观察,并在愈合结束时记录肉芽肿的进展、疤痕类型、形状、大小和临床症状。结果:由于配方具有抗菌、伤口清洁和伤口愈合的特性,治疗过程明显改善。所有患者在使用蜂蜜软膏2-3周后均有显著改善。结论:蜂蜜与羊毛脂联合应用可有效治疗中低度创面。
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