{"title":"Validation of a method of treating menorrhagia by endometrial ablation.","authors":"J H Phipps, T Smith, P Dymek, R Hesp, B V Lewis","doi":"10.1088/0143-0815/13/3/007","DOIUrl":null,"url":null,"abstract":"<p><p>Menstrual blood loss was measured by intravenous injection of radioactive iron (59Fe) and whole-body counting in 19 women complaining of menorrhagia due to dysfunctional bleeding. Fifteen patients were then treated by radiofrequency endometrial ablation, after which blood loss was re-measured. The majority of the patients were bleeding excessively before treatment (mean 281 (SD 156) ml per cycle averaged over two cycles, range 49-665 ml, n = 19). In the 15 treated patients, average blood loss was reduced to 52 (SD 39) ml per cycle and the mean reduction in blood loss was highly significant (P < 0.001). These quantitative data correlate well with the patients' subjective reports.</p>","PeriodicalId":77070,"journal":{"name":"Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics","volume":"13 3","pages":"273-80"},"PeriodicalIF":0.0000,"publicationDate":"1992-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1088/0143-0815/13/3/007","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1088/0143-0815/13/3/007","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Menstrual blood loss was measured by intravenous injection of radioactive iron (59Fe) and whole-body counting in 19 women complaining of menorrhagia due to dysfunctional bleeding. Fifteen patients were then treated by radiofrequency endometrial ablation, after which blood loss was re-measured. The majority of the patients were bleeding excessively before treatment (mean 281 (SD 156) ml per cycle averaged over two cycles, range 49-665 ml, n = 19). In the 15 treated patients, average blood loss was reduced to 52 (SD 39) ml per cycle and the mean reduction in blood loss was highly significant (P < 0.001). These quantitative data correlate well with the patients' subjective reports.
对19例功能性出血所致月经过多的妇女,采用放射性铁(59Fe)静脉注射及全身计数法测定月经失血量。15例患者接受射频子宫内膜消融治疗,术后重新测量出血量。大多数患者在治疗前出血过多(平均每个周期281 ml (SD 156) ml,平均两个周期,范围49-665 ml, n = 19)。在15例接受治疗的患者中,每周期平均失血量减少到52 ml (SD 39),平均失血量减少非常显著(P < 0.001)。这些定量数据与患者的主观报告相吻合。