Diagnosis and treatment of non-allergic rhinitis

Abstract

There is considerable disagreement in the views on the problem of rhinitis, which concerns classification issues, as well as the role and place of various treatment methods. There are no official statistics on non-allergic rhinitis in Russia yet, due to the absence of certain types of rhinitis in the ICD-10. The prevalence of non-allergic rhinitis is one third of the prevalence of allergic rhinitis, involving, for example, in the United States about 7% of the population. Against the background of a convincing evidence base and well-structured international reference documents for allergic rhinitis, other forms of rhinitis, especially non-allergic rhinitis, remain almost “white” spots in medicine, and this leads to numerous errors in the therapeutic approach to this disease. The purpose of this scientific study was to justify the conduct of pathogenic therapy of patients with chronic non-allergic rhinitis by using the differential diagnostic algorithm to establish the etiology of chronic rhinitis. The article formulates a treatment and diagnostic algorithm based on summation of the examination results of 1040 patients with chronic rhinitis. The prevalence and comorbidity of non-allergic rhinitis was determined, the diagnostic value for patients with pseudo-allergic rhinitis of various diagnostic methods (nasocytogramma, prik-test with allergens, biochemical markers of various types of pseudo-allergic rhinitis) was analyzed, and treatment approaches are systematized.