First treatment with venovenous extracorporeal membrane oxygenation in Maribor

Kristjan Skok, A. Markota, F. Svenšek, A. Sinkovič
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Abstract

Purpose: We report on the first patient with refractory hypoxemia treated with venovenous extracorporeal membrane oxygenation (VV ECMO) at the Medical Intensive Care Unit of the University Medical Centre Maribor. Case report: A 52-year-old male was admitted after successful cardiopulmonary resuscitation from out-of-hospital cardiac arrest (first rhythm was ventricular fibrillation, with 40 min to return of spontaneous circulation). The patient underwent primary percutaneous revascularization of the left anterior descendingcoronary artery with insertion of one coronary stent. Hypoxemia was present during patient transportation and the procedure and continued to worsen after admission. Due to refractory hypoxemia caused by aspiration pneumonia, treatment with the VV ECMO was initiated. The ECMO procedure wasperformed without complications and led to improvement in gas exchange and lung mechanics. The patient was then successfully weaned from ECMO, decannulated, and extubated. After extubation, the patient’s course of treatment was complicated by hospital pneumonia and catheter-related blood stream infection.As his state deteriorated, reintubation was necessary. Despite intensive treatment, the patient died on day 30. Conclusions: Response to the VV ECMO treatment of refractory hypoxemia due to aspiration pneumonia was positive and without complications. In spite of initial improvement, the patient died after several weeks due to recurring infection and septic shock. 
马里博尔首次静脉-静脉体外膜氧合治疗
目的:我们报告了马里博尔大学医学中心重症监护室采用静脉静脉体外膜氧合(VV ECMO)治疗的第一位难治性低氧血症患者。病例报告:一名52岁男性,院外心脏骤停心肺复苏成功后入院(第一心律为心室颤动,40分钟恢复自然循环)。患者接受了左前降冠状动脉经皮血管重建术,并植入了一个冠状动脉支架。患者在转运和手术过程中出现低氧血症,并在入院后继续恶化。由于吸入性肺炎引起的难治性低氧血症,开始使用VV ECMO治疗。ECMO手术无并发症,并改善了气体交换和肺力学。然后成功地从ECMO中脱机,去管,拔管。拔管后,患者的治疗过程因医院肺炎和导管相关血流感染而复杂化。由于他的病情恶化,必须重新插管。尽管进行了强化治疗,但患者于第30天死亡。结论:VV ECMO治疗吸入性肺炎难治性低氧血症反应积极,无并发症。尽管最初有所改善,但由于反复感染和感染性休克,患者在几周后死亡。
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