The Optimization of Adiabatic Pulses with Constant Amplitude Spin-lock for Magnetic Resonance $\mathrm{T}_{1\rho}$ Imaging

2021 IEEE International Conference on Real-time Computing and Robotics (RCAR) Pub Date : 2021-07-15 DOI:10.1109/RCAR52367.2021.9517352

Yuxin Yang, Zhongmin Chen, Xi Xu, Yuanyuan Liu, Yanjie Zhu, Dong Liang

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引用次数: 1

Abstract

Quantitative magnetic resonance $\mathrm{T}_{1\rho}$ mapping is an important tool for a number of clinical applications, which can be used to obtain useful molecular information from diseased tissue non-invasively and without contrast agents. However, the stability of $\mathrm{T}_{1\rho}$ mapping is vulnerable to the influence of the magnetic field inhomogeneity, causing image artifacts and non-negligible quantization errors. Therefore, approaches using adiabatic pulses are proposed to alleviate the above deficiencies. This study proposes a method to optimize the HS and HSExp adiabatic pulses with constant amplitude spin-lock. The optimized pulse parameters were obtained through simulation which calculated the stability degree of the longitudinal magnetization Mz under a range of off-resonance values, and verified by phantom and in vivo experiments. The results of the experiment showed that the optimized adiabatic spin-lock pulses can achieve acceptable $\mathrm{T}_{1\rho}$-weighted imaging and $\mathrm{T}_{1\rho}$ mapping qualities.

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磁共振成像中恒幅自旋锁绝热脉冲的优化

定量磁共振$\ mathm {T}_{1\rho}$映射是许多临床应用的重要工具，可用于非侵入性和不使用造影剂从病变组织中获得有用的分子信息。然而，$\ mathm {T}_{1\rho}$映射的稳定性容易受到磁场不均匀性的影响，导致图像伪影和不可忽略的量化误差。因此，提出了利用绝热脉冲的方法来缓解上述不足。本研究提出了一种恒幅自旋锁的HS和HSExp绝热脉冲优化方法。通过仿真得到优化后的脉冲参数，计算了纵向磁化Mz在非共振范围内的稳定程度，并通过体模和体内实验进行了验证。实验结果表明，优化后的绝热自旋锁脉冲能获得较好的$\ mathm {T}_{1\rho}$加权成像和$\ mathm {T}_{1\rho}$映射质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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2021 IEEE International Conference on Real-time Computing and Robotics (RCAR)

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