Could Putting the Mesenchymal Stem Cells Technology into Practice Be an Optimistic Therapy for The Critically Ill COVID-19?

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引用次数: 4

Abstract

COVID-19 comes to light, quickly developing status. Daily, we know more about the human new coronavirus (HCoV19), which is extremely infective with heavy pneumonia connected with fast virus reproduction. Emerging in Wuhan China 31 December 2019, the contemporary COVID-19 outbreak has quickly overripe taking place directly between individuals so contagion extending to be a world health emergency at present on pandemic level. The pandemic has had deep impacts on everyday lifetime towards numerous of the world. Presently no therapy, no specified remedies or inoculations are ready to treat the patients with COVID-19 pollution and investigators here and there the globe are jostling to recognize present medication or synthesis that could be functional versus it. Therefore, there is a great unmet requirement for a secure and efficient therapy for COVID-19 contaminated cases, particularly the serious cases. What types of therapies might now assist? What are the lab craft strategies to restraining coronavirus? Ago mid-February, one tactic that has acquired rising attraction is stem cell therapy, curing that have often been saw as a potential magic bullet by despairing patients suffering from degenerative incurable conditions. In plentiful of these diseases, truth has so far to coincide with the hype. The cell based-therapy doings by supporting the body’s precocious refractory reply in an orientation that could goal the coronavirus. Now stem cell-based therapy for COVID-19 is earning incentive in China. The tally of the world emergency has visible governments frequently proclamation the company global to develop in the search for a cure, and the Australian corporate Mesoblast – a global commander in cell-based therapies for a lot of illnesses – are earned recently the approval to start clinical trials of their possess stem cell based product against COVID-19. Taking into consideration that generality of the dead sick people were produced by serious inflammation reaction, it is extremely demanding to advance efficient curative factors and strategies for that cases. I present an accurate lab modality in preparing mesenchymal stem cells (MSCs) which might be a perfect option to cure the seriously sick novel COVID-19 cases. Beneath this situation, I suppose that blood derived MSCs generated from the critically ill novel COVID-19 patient itself (autologous) suggested as a treatment for him. Therefore, my viewpoint spots a modern curative strategy.
间充质干细胞技术的应用能否成为危重患者COVID-19的乐观疗法?
新冠疫情初露端倪,发展态势迅猛。每天,我们对人类新型冠状病毒(HCoV19)的了解越来越多,这种病毒具有极强的传染性,与病毒快速繁殖有关的严重肺炎。当代COVID-19疫情于2019年12月31日在中国武汉爆发,已经迅速成熟,直接在个人之间发生,因此传染目前已成为大流行级别的世界卫生紧急情况。这一流行病对世界上许多人的日常生活产生了深刻影响。目前还没有治疗方法,没有特定的补救措施或接种方法可以治疗COVID-19污染的患者,全球各地的研究人员都在争先恐后地识别现有的药物或合成方法,这些药物或合成方法可能对其起作用。因此,对COVID-19感染病例,特别是重症病例的安全有效治疗存在很大的需求。现在有哪些治疗方法会有所帮助呢?抑制冠状病毒的实验室工艺策略是什么?2月中旬之前,一种越来越吸引人的策略是干细胞疗法,这种疗法常常被患有退行性不治之症的绝望患者视为潜在的灵丹妙药。在这些疾病中,到目前为止,事实与炒作一致。这种基于细胞的疗法通过支持身体早熟的难治性反应来发挥作用,这种反应可以针对冠状病毒。现在,针对COVID-19的干细胞疗法正在中国获得激励。全球紧急情况的记录表明,各国政府经常宣布该公司在全球范围内开发治疗方法,澳大利亚Mesoblast公司——许多疾病的细胞疗法的全球领导者——最近获得批准,开始对其基于干细胞的产品进行临床试验。考虑到病死患者一般都是由严重的炎症反应引起的,因此提出有效的治疗因素和治疗策略是非常必要的。我提出了一种准确的实验室模式来制备间充质干细胞(MSCs),这可能是治疗新型COVID-19重症病例的完美选择。在这种情况下,我认为重症新型COVID-19患者自身(自体)产生的血源性间充质干细胞可以作为治疗方法。因此,我的观点提出了一种现代的治疗策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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