Advances in Research on the Relationship between Glutamine Metabolism and Breast Cancer

Abstract

Breast cancer is the highest incidence of cancer in women. In recent years, the incidence of breast cancer has been climbing, and the age is becoming younger and younger. Recent studies have shown that glutamine metabolism can promote the occurrence and progression of breast cancer, and is related to malignant proliferation, metastasis and drug resistance of breast cancer. Targeting glutamine metabolism is an important strategy for the treatment of breast cancer. This article reviews the mechanism of glutamine metabolism in breast cancer cells and its research progress and therapeutic significance in different molecular subtypes of breast cancer.