“Prevalence, Risk Factors and its Outcome of Gestational Diabetes Mellitus”

A. Siddiquea, M. Akter, S. Rahman
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Abstract

Introduction: Gestational diabetes mellitus (GDM) is a transitory form of diabetes (glucose intolerance) with onset or first recognition during pregnancy. It is a major and growing public health problem in most parts of the world, with a global prevalence of between 2% and 6% (and as high as 20% in high-risk populations). Gestational Diabetes Mellitus (GDM) is a metabolic disorder defined as glucose intolerance with onset or first recognition during pregnancy. These women are at increased risk of adverse maternal and fetal outcome. Therefore, it’s early diagnosis and management is essential for better fetomaternal outcome. Objective: To assess the prevalence, risk factors and its outcome of gestational diabetes mellitus. Materials and Methods: A Prospective hospital based study was carried out at Dept. of Obstetrics & Gynecology, Al Hera Hospital (Private Clinic), Mawna Chowrasta, Sreepur, Gazipur, Bangladesh from June to December 2021. They were given 75gm glucose irrespective of meals and after 2 hours plasma glucose was estimated. GDM was diagnosed when after 2hours plasma glucose was>140mg/dl. All patients with GDM were followed up and treated with diet and /or insulin therapy till delivery. Maternal and fetal risks factors and outcome were evaluated. Results: Prevalence of GDM was 8.2% in my study. Many of the cases diagnosed as GDM had previous history of large baby, still birth or spontaneous abortion. Maternal complications observed were PIH (40%), polyhydramnious (37.7%), while 66.6% had to undergo caesarean section. Preterm labour occurred in 4 case each (8.8%). No complications were observed in 8 cases (17.7%). 28.8% babies had birth weight of >3.5kg and 17.7% were below 2.5 kg. Conclusion: Women with GDM showed an increased risk of obstetrical and fetal complications. Estimation of plasma glucose level using DIPSI criteria is a single step and cost -effective test to screen large number of cases and to diagnose and manage GDM to prevent maternal and fetal complications.
妊娠期糖尿病的患病率、危险因素及其结局
妊娠期糖尿病(GDM)是一种暂时性糖尿病(葡萄糖耐受不良),在妊娠期间发病或首次发现。在世界大多数地区,这是一个日益严重的重大公共卫生问题,全球患病率在2%至6%之间(在高危人群中高达20%)。妊娠期糖尿病(GDM)是一种代谢紊乱,定义为妊娠期发病或首次发现的葡萄糖耐受不良。这些妇女出现不良孕产和胎儿结局的风险增加。因此,早期诊断和治疗对改善胎儿结局至关重要。目的:了解妊娠期糖尿病的患病率、危险因素及预后。材料和方法:一项基于医院的前瞻性研究于2021年6月至12月在孟加拉国加齐浦尔Sreepur Mawna Chowrasta Al Hera医院(私人诊所)妇产科进行。两餐均给予75克葡萄糖,2小时后测定血糖。2小时后血糖>140mg/dl诊断为GDM。对所有GDM患者进行随访,并给予饮食和/或胰岛素治疗,直至分娩。评估母胎危险因素及预后。结果:本研究GDM患病率为8.2%。许多诊断为GDM的病例既往有大胎、死产或自然流产史。产妇并发症为妊高征(40%)、羊水过多(37.7%),66.6%行剖宫产。早产4例(8.8%)。8例(17.7%)无并发症发生。28.8%的婴儿出生体重>3.5kg, 17.7%的婴儿出生体重低于2.5 kg。结论:GDM妇女出现产科和胎儿并发症的风险增加。使用DIPSI标准估计血糖水平是筛选大量病例并诊断和管理GDM以预防母体和胎儿并发症的单步和成本效益测试。
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