[Menadione induction of Ca2+ efflux from the mitochondria and of mediator secretion from the nerve endings].

Abstract

It is shown that menadion increases the rate of Ca2+ efflux from mitochondria which decreases in the presence of ditiotreitol. Menadion at concentration of 50 microM induces Ca2+ efflux from mitochondria and its effect on synaptic transmission is discussed.