Hemodynamics of Mitral Stenosis

A. Saxena
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Abstract

Hemodynamic is the intravascular pressure and flow that circulate blood throughout the body. In both the venous and arterial compartments, variations in pressure and flow will necessarily affect each other. Flow and pressure within and between the arterial and venous compartments are influenced by hemodynamic on a beat-to-beat basis. Hemodynamic values that are treated in one compartment are dependent on the state of the other compartments. There are several curved proximal isovelocity surface areas as the streamlines of flow approach the stenotic orifice. A stenotic valve's spatial flow velocity profile depends on its anatomy, inlet geometry, and degree of flow acceleration. A patient with Mitral Stenosis (MS) experiences a pressure gradient from the left atrium to the left ventricle that propels the flow abruptly across the stenotic orifice. An arc-shaped flow profile is created, and the atrioventricular valve will therefore have a hemi elliptical velocity profile. At the level of narrowed stenotic orifices, high-velocity jets form in laminar flow when it reaches the vena contracta, the narrowest cross-sectional area downstream from the anatomic orifice, the flow profile in cross-section is relatively flat at the jet's origin and remains flat until the jet reaches the anatomic orifice. Distally from the stenotic region, the blood flow becomes disorganized with multiple velocities and directions. Stenotic mitral valves exhibit thickened leaflets with a reduced excursion. In this review, we will discuss the challenges and changes which occur in hemodynamic of MS.
二尖瓣狭窄的血流动力学
血液动力学是指使血液在全身循环的血管内压力和流量。在静脉室和动脉室中,压力和流量的变化必然会相互影响。动脉和静脉间室内部和之间的流量和压力在搏动的基础上受到血流动力学的影响。在一个室中处理的血流动力学值取决于其他室的状态。当流线接近狭窄口时,有几个弯曲的近端等速表面积。狭窄阀的空间流速分布取决于其解剖结构、入口几何形状和流动加速程度。二尖瓣狭窄(MS)患者经历从左心房到左心室的压力梯度,推动血流突然通过狭窄的孔。一个弧形的流动轮廓被创建,因此房室阀将有一个半椭圆的速度轮廓。在狭窄的狭窄孔水平,高速射流以层流形式到达解剖孔下游最窄横截面积的收缩静脉,在射流原点处,横切面的流动剖面相对平坦,直至射流到达解剖孔为止。在狭窄区域的远处,血流变得紊乱,有不同的速度和方向。狭窄的二尖瓣表现为小叶增厚,偏移减小。在这篇综述中,我们将讨论MS在血液动力学方面的挑战和变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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