Birth, Rise, Decline and Revival of Home Hemodialysis – French experience

A. Meyrier
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Abstract

The first publication in 1960 on maintenance hemodialysis was followed in 1963 by some reports on dialysis in the home. The introduction of proportioning pumps and concentrated electrolyte solutions led to developing single-patient machines and safety devices that made home hemodialysis possible.  It was demonstrated in 1964 that home hemodialysis can be done overnight, unattended. This led to a steady rise in the number of patients treated at home. The percentage in France was ≈20% by the end of the seventies, out of a total of  ≈ 6 000.  The decline began when Public Health authorities authorized a program of ‘’limited – care’’ units.  A loophole in the regulations led to a massive transfer of patients to these units and a rapid decline of home HD. The revival can be dated to 2012 with the development of disposable dialysate bags that make low flow daily home HD feasible. Efficacy and tolerability are such that the total number of patients treated at home rose from 307 in 2014 to 374 in 2016, owing to those on daily hemodialysis -  an increase from 55 in 2014 to 374 in 2016 and 448 by the end of 2018. Currently, ≈46 000 patients are hemodialyzed in France.   The % of those treated at home is very low but the trend is to a steady increase.
家庭血液透析的诞生、兴起、衰落与复兴——法国的经验
1960年首次发表维持性血液透析,1963年又有一些关于家庭透析的报道。比例泵和浓缩电解质溶液的引入导致了单病人机器和安全装置的发展,使家庭血液透析成为可能。1964年证明,家庭血液透析可以在夜间进行,无需护理。这导致在家接受治疗的患者数量稳步上升。到70年代末,法国的这一比例约为20%,而总数约为6000人。当公共卫生当局批准了一项“有限护理”单位计划时,这种下降开始了。法规上的漏洞导致大量患者转移到这些单位,家庭高清迅速下降。这种复兴可以追溯到2012年,随着一次性透析袋的发展,使低流量的日常家庭透析成为可能。由于疗效和耐受性,在家治疗的患者总数从2014年的307人增加到2016年的374人,其中包括每天进行血液透析的患者——从2014年的55人增加到2016年的374人,到2018年底增加到448人。目前,法国约有4.6万名患者接受血液透析。在家接受治疗的患者比例很低,但趋势是稳步上升。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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