Non-Modifiable Factors Associated with Medication-Adherence among Stroke Survivors in Lagos State, Nigeria

Johnson F.A., Atulomah N.O., A. I., Nwachukwu B.C., Ajayi O.C.
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Abstract

Stroke is the world's second most common cause of mortality and the third most common cause of morbidity and disability. Recurrent strokes make up a significant number of stroke admissions to the emergency room. This condition is largely preventable by identifying and addressing the risk factors involved. Hence, this study examined the non-modifiable risk factors associated with medication adherence among stroke survivors in Lagos state, Nigeria. A descriptive cross-sectional survey was conducted using a multistage sampling technique, including 386 stroke survivors from 10 stroke rehabilitation facilities in Lagos state. A validated structured interviewer-administered questionnaire was used for data collection. Data were analyzed using descriptive statistics, Chi-square and Binary logistic regression at a significance level of 5%. The participants' mean age was 52.42 ± 12.143. Results showed that participants aged 51-60years were more likely to adhere to their medication than other age groups. The result also showed no association existed between the age of stroke survivors and medication adherence (OR = 1.119, CI = 0.941-1.332, p = 0.549), ethnicity and medication adherence (OR = 1.176, CI 0.89-1.55, p = 0.211), and the gender (OR = 1.147, CI = 0.748-1.761, p = 0.665). However, there is a significant association between number of stroke and medication adherence (OR = 0.699, CI = 0.499-0.980, p = 0.038). This study's findings highlight important gaps in the factors that influence and are associated with medication adherence. Therefore, other non-modifiable factors asides from the ones assessed in this study should be researched.
尼日利亚拉各斯州中风幸存者中与药物依从性相关的不可改变因素
中风是世界上第二大最常见的死亡原因,也是第三大最常见的发病和残疾原因。反复发作的中风在急诊室中占了相当大的比例。通过识别和处理所涉及的风险因素,这种情况在很大程度上是可以预防的。因此,本研究调查了尼日利亚拉各斯州中风幸存者中与药物依从性相关的不可改变的危险因素。采用多阶段抽样技术进行了描述性横断面调查,包括来自拉各斯州10个中风康复机构的386名中风幸存者。数据收集采用了一份经过验证的结构化访谈问卷。数据分析采用描述性统计、卡方和二元logistic回归,显著性水平为5%。参与者平均年龄为52.42±12.143岁。结果显示,51-60岁的参与者比其他年龄段的人更有可能坚持服药。结果还显示,卒中幸存者的年龄与药物依从性(OR = 1.119, CI = 0.941-1.332, p = 0.549)、种族和药物依从性(OR = 1.176, CI = 0.89-1.55, p = 0.211)、性别(OR = 1.147, CI = 0.748-1.761, p = 0.665)之间不存在相关性。然而,卒中次数与药物依从性之间存在显著相关性(OR = 0.699, CI = 0.499-0.980, p = 0.038)。这项研究的发现突出了影响药物依从性和与药物依从性相关的因素的重要差距。因此,除了本研究评估的因素外,还需要研究其他不可改变的因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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