Infections Caused By S. aureus MRSA and Natural Antimicrobial Mechanisms to Reduce These Contaminants

R. Nunes, R. Assumpção, Brenda Silva de Lima, Ynis Cristine de Santana Martins Lino Ferreira
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Abstract

The advance of S.aureus infections, strain/clone identification methods prevalent in hospitals and resistant to antimicrobials needs to be rapidly effective due to the shortage of new antimicrobial agents. Objective: of this work is to perform a literature review on the epidemiology of methicillin-resistant strains of S.aureus in circulation in Brazil. An integrative literature review was used, which allows summarizing previous research and obtaining general conclusions from them to analyze the scientific knowledge on the subject to be investigated. Methodology:The databases consulted were Latin American and Caribbean Health Sciences Literature (LILACS), International Health Sciences Literature (PubMed), Scientific Electronic Library Online (SCIELO). Literature Review: dissemination in Brazil are: Brazilian epidemic clone (ST239/SCCmecIII) and the Pediatric clone (USA400), are in circulation in hospitals in Brazil, these present a genetic pattern of virulence factors (SCC mec I to IV), PVL proteins, among others, differentiated between them and the Brazilian region with more studies is the Southeast region. Conclusion: Studies are needed to provide greater knowledge about the molecular epidemiology, evolution and antimicrobial resistance of methicillin-resistant S. aureus clones in Brazil, especially in the North and Northeast regions of the country.
金黄色葡萄球菌MRSA引起的感染和减少这些污染物的天然抗菌机制
由于缺乏新的抗微生物药物,金黄色葡萄球菌感染的进展、医院流行的菌株/克隆鉴定方法和对抗微生物药物的耐药性需要迅速发挥作用。目的:对巴西流行的耐甲氧西林金黄色葡萄球菌的流行病学进行文献综述。使用综合文献综述,可以总结以前的研究并从中获得一般结论,以分析待调查主题的科学知识。方法:咨询的数据库包括拉丁美洲和加勒比卫生科学文献(LILACS)、国际卫生科学文献(PubMed)、科学电子图书馆在线(SCIELO)。文献综述:在巴西的传播有:巴西流行病克隆(ST239/SCCmecIII)和儿科克隆(USA400),在巴西的医院中流通,这些克隆呈现出毒力因子(SCC mecI至IV)、PVL蛋白等的遗传模式,它们与巴西地区有区别,研究较多的是东南部地区。结论:巴西特别是北部和东北部地区耐甲氧西林金黄色葡萄球菌克隆的分子流行病学、进化和耐药情况有待进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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